Hi all,
I have a large number of bam files from multiple individuals. I need to call snps on them using mpileup. When I sort and index with samtools, the I/O goes crazy on my cluster. Is the sorting/indexing necessary or does it just speed things up?
Thanks,
I have a large number of bam files from multiple individuals. I need to call snps on them using mpileup. When I sort and index with samtools, the I/O goes crazy on my cluster. Is the sorting/indexing necessary or does it just speed things up?
Thanks,
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