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  • [Help] What is a "Unigene" ?

    Hello,

    I don't understand precisely what is a "Unigene"

    I have been looking intensively on the internet but I always get "NCBI Unigene database" as a result, I didn't found any definition of what is a Unigene.

    According to my comprehension, a Unigene is a cDNA sequence that can produce all the different mRNA that have been found to be related to that cDNA sequence... but I feel confused about it....

    Thanks a lot in advance,

    M.
    Last edited by Meligethes; 08-21-2012, 05:58 AM. Reason: bad sentence construction

  • #2
    From the NCBI Unigene site

    "UniGene computationally identifies transcripts from the same locus; analyzes expression by tissue, age, and health status; and reports related proteins (protEST) and clone resources"

    Details of build procedures for the two flavors of Unigene:
    Genome-based http://www.ncbi.nlm.nih.gov/UniGene/...gi?item=build2
    Transcript-based http://www.ncbi.nlm.nih.gov/UniGene/...gi?item=build1

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    • #3
      Awesome, thank you !!

      Comment


      • #4
        i still wonder how to figure out unigenes for a complete genome by NCBI

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        • #5
          Originally posted by bagaric View Post
          i still wonder how to figure out unigenes for a complete genome by NCBI
          You can use the "Limits" option in Unigene search and then choose the organism field to limit the search for a specific genome (attached image shows human).

          Or "limiting" the search by taxonomy ID may be better (e.g. 6239 for C. elegans). You can find the taxonomy ID's here: http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi
          Attached Files
          Last edited by GenoMax; 03-19-2014, 04:00 AM.

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