Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • lher
    started a topic sequence bias correction in base coverage calculation

    sequence bias correction in base coverage calculation

    Hi,

    I have 76 bp Illumina HiSeq yeast mRNA seq data and would like to do a combined analysis of sequence coverage over a set of ~500 transcripts, which are all aligned in a range from 1 to 1000.
    However, the combined coverage profile is still noisy and shows many artificial peaks.
    Is there a way to account for sequencing biases and then modify the genome coverage file (e.g. bedgraph) respectively?

    Thanks for any suggestions!

Latest Articles

Collapse

  • seqadmin
    Non-Coding RNA Research and Technologies
    by seqadmin


    Non-coding RNAs (ncRNAs) do not code for proteins but play important roles in numerous cellular processes including gene silencing, developmental pathways, and more. There are numerous types including microRNA (miRNA), long ncRNA (lncRNA), circular RNA (circRNA), and more. In this article, we discuss innovative ncRNA research and explore recent technological advancements that improve the study of ncRNAs.

    [Article Coming Soon!]...
    Today, 08:07 AM
  • seqadmin
    Recent Developments in Metagenomics
    by seqadmin





    Metagenomics has improved the way researchers study microorganisms across diverse environments. Historically, studying microorganisms relied on culturing them in the lab, a method that limits the investigation of many species since most are unculturable1. Metagenomics overcomes these issues by allowing the study of microorganisms regardless of their ability to be cultured or the environments they inhabit. Over time, the field has evolved, especially with the advent...
    09-23-2024, 06:35 AM
  • seqadmin
    Understanding Genetic Influence on Infectious Disease
    by seqadmin




    During the COVID-19 pandemic, scientists observed that while some individuals experienced severe illness when infected with SARS-CoV-2, others were barely affected. These disparities left researchers and clinicians wondering what causes the wide variations in response to viral infections and what role genetics plays.

    Jean-Laurent Casanova, M.D., Ph.D., Professor at Rockefeller University, is a leading expert in this crossover between genetics and infectious...
    09-09-2024, 10:59 AM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by seqadmin, 10-02-2024, 04:51 AM
0 responses
14 views
0 likes
Last Post seqadmin  
Started by seqadmin, 10-01-2024, 07:10 AM
0 responses
24 views
0 likes
Last Post seqadmin  
Started by seqadmin, 09-30-2024, 08:33 AM
1 response
31 views
0 likes
Last Post EmiTom
by EmiTom
 
Started by seqadmin, 09-26-2024, 12:57 PM
0 responses
19 views
0 likes
Last Post seqadmin  
Working...
X