SVA is just released!
Check it out at: http://www.svaproject.org/
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SequenceVariantAnalyzer: analyzing genetic variants from next-gen sequencing
Friends,
If you are working on next-generation sequencing studies, particularly if you are interested in annotating, visualizing SNPs, INDELs, CNVs, and identifying genetic variants responsible for biological traits or diseases, please check out our software tool SequenceVariantAnalyzer (SVA):
SVA is designed for two specific aims:
- To annotate the biological functions of the identified genetic variants, organize and visualize them;
- To help find the genetic variants that are associated with or responsible for the biological traits or medical outcomes of interest.
The SVA release package comes with an example project extracted from 10 genomes - 5 cases and 5 controls. To reduce the size of the release package, I release only the data on chromosome X. The web page below shows that you can play with SVA and an example project to "identify (again )" the Factor VIII (F8) gene for type A hemophilia:
SVA is also featured with an integrated genome browser to help an investigator to explore the user-generated data and data from public domains. Here is a screenshot:
Particularly, SVA genome browser allows you to conveniently 'introduce' key variants that you identified to compare and see the difference they could make.
Please give it a try and let us know what you think.
Lastly, I hope you may find this tool helpful for your next-generation discovery!
Best regards,
Dongliang Ge,
Duke University, USA
Last edited by Dongliang Ge; 03-04-2010, 02:26 PM.
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