hg18 downloaded from ucsc consits of lower-case letters like a c g t.
human build 36 downloaded from ncbi consits of A C G T N.
Could anyone kindly tell me how bwa and bowtie deal with the Ns and lower-case letters when they map reads to the references?
Best
human build 36 downloaded from ncbi consits of A C G T N.
Could anyone kindly tell me how bwa and bowtie deal with the Ns and lower-case letters when they map reads to the references?
Best
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