Hey all,
I'm back in the nextgen sequencing game for this summer. Working with methylation data for the first time. I have a series of cases and controls of MBD-seq data and would like to find differentially methylated peaks/regions between the two, and additionally I want to simply be able to call peaks in any given sample. Are there any standard peak callers out there that are good for this type of thing (or is there a good review that covers this to some degree)? I would very much appreciate any input.
I'm back in the nextgen sequencing game for this summer. Working with methylation data for the first time. I have a series of cases and controls of MBD-seq data and would like to find differentially methylated peaks/regions between the two, and additionally I want to simply be able to call peaks in any given sample. Are there any standard peak callers out there that are good for this type of thing (or is there a good review that covers this to some degree)? I would very much appreciate any input.
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