Hi :
Anybody can help me ?
I am computing the relative DNA methylated Cytosine density of genome, and
confused by the following question:
the DNA sequence is AACGCTT and the methylation level of CGC are 0.6, 0.8,1.0 respectively. Now, is the retio of mCG values to total numbers of CGs
is (0.6+0.8)/2=0.7 or (0.8+1.0)/2=0.9 or (0.6+0.8+1.0)/3=0.8 or [(0.6+0.8)/2+(0.8+1.0)/2]/2=0.8 ? which is correct among the four methods ?
thanks
Anybody can help me ?
I am computing the relative DNA methylated Cytosine density of genome, and
confused by the following question:
the DNA sequence is AACGCTT and the methylation level of CGC are 0.6, 0.8,1.0 respectively. Now, is the retio of mCG values to total numbers of CGs
is (0.6+0.8)/2=0.7 or (0.8+1.0)/2=0.9 or (0.6+0.8+1.0)/3=0.8 or [(0.6+0.8)/2+(0.8+1.0)/2]/2=0.8 ? which is correct among the four methods ?
thanks
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