It might be a naive question:
After aligning agaist a reference genome, we can get sorted consensus sequences for each chromosome. My question is how to integrate the unmapped reads to generarte a distinct whole genome sequence?
Is De novo assembly of all the reads (mapped and unmapped, paired-end and single-end) doing this job?
Thanks
After aligning agaist a reference genome, we can get sorted consensus sequences for each chromosome. My question is how to integrate the unmapped reads to generarte a distinct whole genome sequence?
Is De novo assembly of all the reads (mapped and unmapped, paired-end and single-end) doing this job?
Thanks
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