We develop a GUI software tool for processing SAM files. The software allows users to accurately estimate gene expression scores using short reads originating from both exons and exon-exon junctions, to generate wiggle files for visualization in UCSC genome browser, and to generate an alignment statistics report. This GUI tool will facilitate the downstream analysis of genomic sequencing data.
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SAMMate documentation
Hi xuguorong,
found it. Many thanks. I'll let you know how we get on with it here at SBL
(www.sbl-uk.org).
Mike
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The complexity of cancer is clearly demonstrated in the diverse ecosystem of the tumor microenvironment (TME). The TME is made up of numerous cell types and its development begins with the changes that happen during oncogenesis. “Genomic mutations, copy number changes, epigenetic alterations, and alternative gene expression occur to varying degrees within the affected tumor cells,” explained Andrea O’Hara, Ph.D., Strategic Technical Specialist at Azenta. “As...-
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