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dear All,
I'd like to compare 6 gene expression datasets (multiple conditions / time-points) in terms of joint patterns in the enrichments of the differentially expressed genes. The gene lists I have prepared (including logFC, padj). GO and KEGG enrichments would be nice, the more options the better. All should be doable via a Webserver. And the enrichment method should be state-of-the-art, GSEA may be a very good choice. The geneset databases should be up-to-date.
Long ago, I used ToppCluster, which I liked because I could simultanously enter all the datasets, and it returned similar enrichments in some of the datasets in a nice table.
georg
I'd like to compare 6 gene expression datasets (multiple conditions / time-points) in terms of joint patterns in the enrichments of the differentially expressed genes. The gene lists I have prepared (including logFC, padj). GO and KEGG enrichments would be nice, the more options the better. All should be doable via a Webserver. And the enrichment method should be state-of-the-art, GSEA may be a very good choice. The geneset databases should be up-to-date.
Long ago, I used ToppCluster, which I liked because I could simultanously enter all the datasets, and it returned similar enrichments in some of the datasets in a nice table.
- Are there other good options, maybe better ones? Optimally, the tool allows further useful analyses and visualizations.
- For the time-series, considering the temporal aspect explicitly would be nice, but usually the first and the last time-point are most informative so that it boils down to two conditions.
georg