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  • Tomas
    Junior Member
    • May 2024
    • 1

    #1

    genome finishing

    I'm new to bioinformatics so I apologize in advance. I have a pipeline for genome assembly, the output I get is a de novo assembly file SPAdes, contigs.fasta, as well as a variant file vcf.fasta, I need to use the information about the variants from vcf.fasta and make these changes to contig.fasta, correct do I think? if yes, how can I do it better? I need to somehow combine information from vcf.fast and contigs.fast to get a consensus sequence.

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