Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • buthercup_ch
    Member
    • Apr 2014
    • 41

    #1

    Identification and grouping of ortholog protein from a set of prokaryotic genomes

    Hi everyone.

    In the frame of a project of comparative genomics, I have right now a set of about 30 whole-genome sequences of bacteria, of about 3-4 Gb size, and need to retrieve orthologous groups of proteins. The idea is to identify common and specific proteomes.

    A former bioinformatician used to use CD-HIT to do so, but I also heard about OrthoMCL.

    Do you know about other "non bioinformatician-friendly" software or bioinformatic tool easy to use?

    I'm not bioinformatician but I'm starting now to introduce in the world of bioinformatics: RSudio, R/Bioconductor, Python… I'm really far by now of dominate all that, but if someone can give me any advice concerning my problem, it will be really appreciated.

    Also, if you know someone experienced in this kind of analysis willing to open a formal collaboration, please, also let me know.

    Thank you in advance!!
  • WhatsOEver
    Senior Member
    • Apr 2012
    • 215

    #2
    I have had good experience with proteinortho (https://www.bioinf.uni-leipzig.de/So.../proteinortho/)
    Personally, I think it is one of the "easy to use" tools you're looking for

    Comment

    Latest Articles

    Collapse

    • SEQadmin2
      16S/ITS Profiling vs. Shotgun Metagenomics: What Changes in Your Workflow?
      by SEQadmin2




      NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...
      Today, 06:46 AM
    • SEQadmin2
      Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
      by SEQadmin2



      Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

      Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating
      ...
      10-14-2026, 09:55 AM

    ad_right_rmr

    Collapse

    News

    Collapse

    Topics Statistics Last Post
    Started by SEQadmin2, 10-28-2026, 09:57 AM
    0 responses
    22 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 10-28-2026, 09:51 AM
    0 responses
    14 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 10-22-2026, 11:13 AM
    0 responses
    67 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 10-22-2026, 10:48 AM
    0 responses
    47 views
    0 reactions
    Last Post SEQadmin2  
    Working...