Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Median basepair coverage of reads across contig length

    Hello experts,

    I am having hard time to understand a method from a metagenomic paper. The author used "median basepair coverage of reads across contig length" to measure base pair coverage of contigs. Does this mean that reads were aligned to contigs and length of contigs covered by reads were used? What does median mean here? Could anyone give me more detailed explanation on this? Any advice would be greatly appreciated.
    Last edited by morning latte; 12-22-2014, 07:07 AM.

  • #2
    Perhaps if you give us a reference to the paper then we could figure out what the author meant.

    As a wild guess since this is metagenomics thus implying multiple read sets aligned to each contig, I think that (1) the reads were aligned and (2) a coverage per contig per read set was obtained and then (3) a median per contig was found for all of the read sets. But as I say that an wild guess.

    Comment

    Latest Articles

    Collapse

    • seqadmin
      Multiomics Techniques Advancing Disease Research
      by seqadmin


      New and advanced multiomics tools and technologies have opened new avenues of research and markedly enhanced various disciplines such as disease research and precision medicine1. The practice of merging diverse data from various ‘omes increasingly provides a more holistic understanding of biological systems. As Maddison Masaeli, Co-Founder and CEO at Deepcell, aptly noted, “You can't explain biology in its complex form with one modality.”

      A major leap in the field has
      ...
      02-08-2024, 06:33 AM
    • seqadmin
      The 3D Genome: New Technologies and Emerging Insights
      by seqadmin


      The study of three-dimensional (3D) genomics explores the spatial structure of genomes and their role in processes like gene expression and DNA replication. By employing innovative technologies, researchers can study these arrangements to discover their role in various biological processes. Scientists continue to find new ways in which the organization of DNA is involved in processes like development1 and disease2.

      Basic Organization and Structure
      Understanding...
      01-22-2024, 03:25 PM

    ad_right_rmr

    Collapse

    News

    Collapse

    Topics Statistics Last Post
    Started by seqadmin, Yesterday, 08:57 AM
    0 responses
    12 views
    0 likes
    Last Post seqadmin  
    Started by seqadmin, 02-14-2024, 09:19 AM
    0 responses
    43 views
    0 likes
    Last Post seqadmin  
    Started by seqadmin, 02-12-2024, 03:37 PM
    0 responses
    408 views
    0 likes
    Last Post seqadmin  
    Started by seqadmin, 02-09-2024, 03:36 PM
    0 responses
    648 views
    0 likes
    Last Post seqadmin  
    Working...
    X