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  • vitor
    Junior Member
    • Apr 2015
    • 5

    #1

    Analysis of SNP in viral genome

    I'm analyzing mutations (SNPs) in the genome of a ssDNA virus (virus X and Y)
    I had sequenced the total DNA in Illumina plataform HiSeq 2000 and I got the reads in FASTA format.

    I want:
    The reads filtered;
    The reads mapped in reference genome.

    I need
    A program or tool to discovered the SNPs among the genome with reliability;
    or/and some statistics to apply them;
    and a statistic method to explain when a viral DNA (virus X) is higher than viral DNA (virus Y) in the same organism (probably the virus X replies more than the other, because the virus X has higher coverage than virus Y).

    Thanks!

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