Hi,
I am just wondering what human references you will use when you try to align your reads to human genome.
Will you use the reference including chr randoms ?
I am asking this question because if we do not use chr randoms, the alignment may generate more false positive signals, if we use them, the total reads can be used for finished ref will be lessor.
Who have compared these results? Thanks.
I am just wondering what human references you will use when you try to align your reads to human genome.
Will you use the reference including chr randoms ?
I am asking this question because if we do not use chr randoms, the alignment may generate more false positive signals, if we use them, the total reads can be used for finished ref will be lessor.
Who have compared these results? Thanks.