I used MAQ as an aligner for reads from ABI SOLiD. However, the flag from mapping results or sam file (converted from mapping results) shows difference with what I did for GA2. For example, the flag values of 18, 64 and 128 in GA2 results were shown as 17, 65, and 129 in SOLiD results. Has anyone encountered the same problem and how to fix it?
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM