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  • mrawlins
    started a topic GeneSifter for RNA-Seq

    GeneSifter for RNA-Seq

    Has anyone used GeneSifter for RNA-Seq data? It looks like it takes care of mapping, splicing detection and visualization. There's a lot of good functions there, but I'm not sure how well they're implemented.

    My first concern is that uploading the full csfasta to their web servers will take a long time.
    My second concern is that the statistics they list are basically just variations on the t-test, which in our experience don't work really well for RNA-Seq data. We've got a data normalization process and corresponding statistical test that works quite well. GeneSifter appears to allow for extensions, and I'm wondering if it allows for that level of customization.
    My only other question (not so much a concern) is how their algorithms differ from those in the open source alternatives.

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  • seqadmin
    Multiomics Techniques Advancing Disease Research
    by seqadmin


    New and advanced multiomics tools and technologies have opened new avenues of research and markedly enhanced various disciplines such as disease research and precision medicine1. The practice of merging diverse data from various ‘omes increasingly provides a more holistic understanding of biological systems. As Maddison Masaeli, Co-Founder and CEO at Deepcell, aptly noted, “You can't explain biology in its complex form with one modality.”

    A major leap in the field has
    ...
    02-08-2024, 06:33 AM

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