Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • A problem with Elastic net + Cox regression

    I was trying to perform elastic net + cox regression in R using the glmnet package. The problem is that my data is around 100 individuals with ~100k features and the model is too big for R to store in a matrix. Although the glmnet package can use sparse matrix for the model unfortunately it does not support it with Cox regression.

    Anyone knows of another tool I can use (I am not locked in R, it was just the only tool I found)? I read that I can use an SVM (support vector machine) but I still need to calculate the model. I am looking for any tool (R, Matlab, stand alone application) that can perform elastic net + cox regression on a big model. Furthermore, maybe you know how to calculate this big model as a stand alone output so I can use it in an SVM?

  • #2
    For reference cross-posted: https://www.biostars.org/p/176689/

    Comment


    • #3
      I am sorry, I did not know that it is against the rules to post in multiple forums the same question. Not to make another post on this: I will mention if on the other forum the question in answered.
      Last edited by Anastaziel; 02-11-2016, 04:13 PM.

      Comment


      • #4
        Originally posted by Anastaziel View Post
        I am sorry, I did not know that it is against the rules to post in multiple forums the same question.
        No it is not against the rules so don't worry.

        I included the link so people can see if your question has been answered on Biostars before they compose a lengthy response (if one was needed) here.

        You can help by coming back and posting a closure if your question is answered on Biostars.

        Comment


        • #5
          I was able to fix my problem. I was using a wrong test case and my model was becoming too big. Using the example from glment.pdf fixes the issue.

          Comment

          Latest Articles

          Collapse

          • seqadmin
            Latest Developments in Precision Medicine
            by seqadmin



            Technological advances have led to drastic improvements in the field of precision medicine, enabling more personalized approaches to treatment. This article explores four leading groups that are overcoming many of the challenges of genomic profiling and precision medicine through their innovative platforms and technologies.

            Somatic Genomics
            “We have such a tremendous amount of genetic diversity that exists within each of us, and not just between us as individuals,”...
            05-24-2024, 01:16 PM
          • seqadmin
            Recent Advances in Sequencing Analysis Tools
            by seqadmin


            The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...
            05-06-2024, 07:48 AM

          ad_right_rmr

          Collapse

          News

          Collapse

          Topics Statistics Last Post
          Started by seqadmin, Yesterday, 06:55 AM
          0 responses
          12 views
          0 likes
          Last Post seqadmin  
          Started by seqadmin, 05-30-2024, 03:16 PM
          0 responses
          24 views
          0 likes
          Last Post seqadmin  
          Started by seqadmin, 05-29-2024, 01:32 PM
          0 responses
          29 views
          0 likes
          Last Post seqadmin  
          Started by seqadmin, 05-24-2024, 07:15 AM
          0 responses
          215 views
          0 likes
          Last Post seqadmin  
          Working...
          X