Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Querying with VCF Tools

    Hello. I have some VCF files which I will be working with. Today I came across a tool named VCF Tools and it seems like it might be useful. However, before I download and install it, I was wondering if it will be able to answer all of the following case scenarios or should I build my own program to parse my files?

    Case Scenario 1:

    All known (have an RS id) polymorphic positions for sample IDs starting with P0048* with AF<0.10.

    Case Scenario 2:

    All unknown polymorphic positions for sample IDs starting with P0048* with AF<0.10.

    Case Scenario 3:

    All known (have an RS id) polymorphic positions for sample IDs starting with P0048* with AF<0.10. Report the genotypes for all individuals in the family that have a coverage for those positions greater than 20 (i.e. DP >20) for individuals with DP <20 replace genotype with ./.

    Thanks!

Latest Articles

Collapse

  • seqadmin
    Best Practices for Single-Cell Sequencing Analysis
    by seqadmin



    While isolating and preparing single cells for sequencing was historically the bottleneck, recent technological advancements have shifted the challenge to data analysis. This highlights the rapidly evolving nature of single-cell sequencing. The inherent complexity of single-cell analysis has intensified with the surge in data volume and the incorporation of diverse and more complex datasets. This article explores the challenges in analysis, examines common pitfalls, offers...
    Today, 07:15 AM
  • seqadmin
    Latest Developments in Precision Medicine
    by seqadmin



    Technological advances have led to drastic improvements in the field of precision medicine, enabling more personalized approaches to treatment. This article explores four leading groups that are overcoming many of the challenges of genomic profiling and precision medicine through their innovative platforms and technologies.

    Somatic Genomics
    “We have such a tremendous amount of genetic diversity that exists within each of us, and not just between us as individuals,”...
    05-24-2024, 01:16 PM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by seqadmin, Today, 08:18 AM
0 responses
8 views
0 likes
Last Post seqadmin  
Started by seqadmin, Today, 08:04 AM
0 responses
10 views
0 likes
Last Post seqadmin  
Started by seqadmin, 06-03-2024, 06:55 AM
0 responses
13 views
0 likes
Last Post seqadmin  
Started by seqadmin, 05-30-2024, 03:16 PM
0 responses
27 views
0 likes
Last Post seqadmin  
Working...
X