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  • #31
    "it depends on the data in question". I suggest remove duplicates and see how it affects the overall quality. Then, decide weather removing duplicates is useful.

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    • #32
      Assemblers use coverage to determine things like how many copies of a repeat there are and whether a base is an error or not. Removing duplicates can effect this; it could increase or decrease the quality of the assembly. Are you using PCR-amplified data?

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