I have FPKM values for 3 tissues and no biological replicates (this is 2nd hand data) I want to get a rough idea (giving the lack of replicates) of which genes are differentially expressed prior to doing real time quantitative PCR. Is there anything i should be doing other than looking for fold changes above a specified level?
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM
