Hello,
I'm currently interested in CNV (Copy Number Variation, but I'm sure you're familiar ) detection, and I wonder
1. what software tools exist for this application? I've seen one package so far, found here on SEQanswers: http://tiger.dbs.nus.edu.sg/cnv-seq/ Copyright © 2009 Xie Chao @ Tammi Lab.
2. if other tools can be used for CNV detections. I mean, there are quite a few ChIPSeq analysis tools, which are designed for detecting "peaks": prominent read densities compared to a background read level. The idea behind CNV is basically the same...
(Although I know that some ChIPSeq tools certainly can't be used for CNV, because of their underlying detection concept, like looking for pair of peaks etc.)
Please share your thoughts! Thanks,
Miklos
I'm currently interested in CNV (Copy Number Variation, but I'm sure you're familiar ) detection, and I wonder
1. what software tools exist for this application? I've seen one package so far, found here on SEQanswers: http://tiger.dbs.nus.edu.sg/cnv-seq/ Copyright © 2009 Xie Chao @ Tammi Lab.
2. if other tools can be used for CNV detections. I mean, there are quite a few ChIPSeq analysis tools, which are designed for detecting "peaks": prominent read densities compared to a background read level. The idea behind CNV is basically the same...
(Although I know that some ChIPSeq tools certainly can't be used for CNV, because of their underlying detection concept, like looking for pair of peaks etc.)
Please share your thoughts! Thanks,
Miklos
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