Pipelines for low coverage genomes - SEQanswers

You are currently viewing the SEQanswers forums as a guest, which limits your access. Click here to register now, and join the discussion

X

oiiio

Senior Member

Join Date: Jan 2011

Posts: 105
- Share
- Tweet
#1

Pipelines for low coverage genomes

02-07-2020, 10:32 AM

For whole genome sequencing at 1x or below, does anyone have a pipeline that they get results that they trust with?

Ideally this would include and aligner, variant caller, imputation tool, and any preprocessing steps in between. For example BWAMEM, PICARD, GATK, IMPUTE2.
Tags: None

Previous template Next

Essential Discoveries and Tools in Epitranscriptomics

by seqadmin

The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...
- Channel: Articles
04-22-2024, 07:01 AM
Current Approaches to Protein Sequencing

by seqadmin

Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
- Channel: Articles
04-04-2024, 04:25 PM

	Topics		Statistics	Last Post
	Genetic Variants and Diabetes Risk in Childhood Cancer Survivors by seqadmin Started by seqadmin, Yesterday, 08:47 AM		0 responses 13 views 0 likes	Last Post by seqadmin Yesterday, 08:47 AM
	Cancer Metastasis: A Deep Dive into Cellular Plasticity by seqadmin Started by seqadmin, 04-11-2024, 12:08 PM		0 responses 60 views 0 likes	Last Post by seqadmin 04-11-2024, 12:08 PM
	Proteogenomic Profiles Offer New Clues in Prostate Cancer by seqadmin Started by seqadmin, 04-10-2024, 10:19 PM		0 responses 60 views 0 likes	Last Post by seqadmin 04-10-2024, 10:19 PM
	Novel Diagnostic Assay Enhances Ovarian Cancer Detection by seqadmin Started by seqadmin, 04-10-2024, 09:21 AM		0 responses 54 views 0 likes	Last Post by seqadmin 04-10-2024, 09:21 AM

Working...

X