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It's unlikely that the underlying aligner would have run at different speeds on different systems since they're both going to be calling out to the same code. It seems more likely that the aligners were run with different parameters (different levels of multi-threading, different alignment stringencies etc) which can have a big effect on how long they take to process their data.
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No, I ran them with the exact same parameters.Comment
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I think that CLC GW is pretty good - we've had it hear for over a year.Comment
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Strand NGS, the integrated analysis platform
Strand NGS (Formerly Avadis NGS) is an integrated platform that provides analysis, management and visualization tools for next-generation sequencing data. It supports extensive workflows for alignment, RNA-Seq, small RNA-Seq, DNA-Seq, Methyl-Seq, MeDIP-Seq, and ChIP-Seq experiments.
Pipeline manager option can be used to streamline large scale analysis.
More details on various enhancements/features can be found at http://www.strand-ngs.com/featuresComment
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Strand NGS has improved a lot. The user interface is similar to that of Agilent Technologies GeneSpring, since it is built on same platform Avadis. Strand NGS is very flexible, since its interface auto-adopts to experiment type, only showing relevant analysis steps and functions (i.e guided workflows). You can also customize via R scripts and Jython scripts. Annotation Manager provides access to annotations from within the tool and many moreComment
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...04-22-2024, 07:01 AM -
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM
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