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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
105,472 views
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by Guest
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
673,300 views
1 like
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Last Post
by ECO
12-25-2009, 06:45 PM
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Started by OYA, 12-02-2022, 01:37 AM
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0 responses
105 views
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by OYA
12-02-2022, 01:37 AM
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NGS Data Analysis: A Practical Introduction (December 12-14, 2022 in Munich, Germany)
by ecSeq Bioinformatics
Started by ecSeq Bioinformatics, 11-30-2022, 07:56 AM
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0 responses
99 views
0 likes
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Last Post 11-30-2022, 07:56 AM | ||
Started by uhrigs, 02-15-2018, 12:53 PM
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11 responses
7,881 views
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Last Post
by uhrigs
11-29-2022, 06:10 AM
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Started by MAAJID, 11-24-2022, 06:36 AM
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0 responses
96 views
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Last Post
by MAAJID
11-24-2022, 06:36 AM
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Started by fabio.marcelo, 08-20-2019, 06:30 PM
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3 responses
2,577 views
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Last Post
by vihan
11-20-2022, 10:59 PM
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Started by Masklin, 10-19-2022, 02:25 AM
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5 responses
193 views
2 likes
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Last Post
by Shina
11-18-2022, 02:26 PM
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Started by ecSeq Bioinformatics, 10-05-2022, 05:34 AM
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2 responses
190 views
0 likes
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Last Post 11-14-2022, 12:49 AM | ||
Started by ehlannom, 11-10-2022, 09:16 AM
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2 responses
260 views
1 like
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Last Post
by ehlannom
11-11-2022, 10:47 AM
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Started by jjbox, 11-11-2022, 07:33 AM
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0 responses
106 views
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Last Post
by jjbox
11-11-2022, 07:33 AM
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Started by roobcf, 11-07-2022, 09:25 AM
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1 response
138 views
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Last Post
by Michael.Ante
11-11-2022, 05:34 AM
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
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Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...-
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