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  • PNAS: the first recombinant protein drug carrier

    Looking for a drug may be sent to the target in the body of a biocompatible carrier inevitably many significant challenges. In addition to manufacturingand load the carrier and other practical problems, the carrier must also betogether with the drugs play an effective role, and taking safety. Like hollow capsule double bubble like (vesicles) is the ideal choice, because the bodynaturally produces similar structure compounds transported from one place to another place. However, finding a suitable molecular assembly into capsule, currently there are still difficulties. Now, researchers from the University of Pennsylvania have developed a new method can be used to generate carrier, and fine tune their shape. They use a protein found insunflower seeds, through genetic engineering technology to produce a variety of can be assembled into proteins vesicles or other useful structure.This study published in the proceedings of the National Academy of Sciences "USA" (PNAS).
    "To our knowledge, this is the first made of vesicles,"University of Pennsylvania professor Daniel A. Hammer says the biological engineering.
    The recombinant protein is a technique for the generally acceptedproducts. This technology relates to a gene into a host organism designed in (in most cases is Escherichia coli), so that the organism to generatenormally not protein synthesis.
    The Hammer team in the past ten years searching for a protein, the biocompatibility, can be generated by recombinant methods, the most important thing is to be induced vesicle formation. Biologicalwww.ebiotrade.com
    Hammer said: "we found that a copeptin elisa kit[/url] called oleosin. It is the surfactant protein A in sunflower seeds, and sesame seeds."
    Last edited by banannababy; 06-15-2014, 05:37 PM.

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