Originally posted by ECO
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Moving to ....um...general?
You can guess at the origin of replication as the coverage may be higher there if you were to sequence a dividing population. I've seen this in bacterial datasets. I would guess that unless the plasmid is very large that you'd have a hard time detecting the overabundance of replication near the ori.
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how to detect ori of plasmid
hi, I want to predict ori of a plasmid. but it sems there is not a good method for plasmid. we can use GC skew to find ori of genome. is it available for plasmid.
In addition, I found it is vary slowly to open up SEQanswers web in china. does anyone have the same question?
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