We are recruiting a Postdoctoral Associate to identify and experimentally characterize human-specific changes in developmental gene regulation by integrated analysis of RNA-seq, ChIP-seq and other functional genomics datasets. This project will build on our previous efforts using both comparative genomics to identify human-specific enhancer functions (e.g., Science 321: 1346 (2008)), and comparative epigenomics to directly study regulatory functions in homologous embryonic tissues (e.g., Cell 154:185 (2013)). Candidates must have a Ph.D. in Genetics or a related field, as well as significant experimental expertise in functional genomics. Candidates with experience in implementing massively parallel enhancer assays will be highly competitive for this position. Interested candidates should send their CV and references to Jim Noonan at [email protected]. Please include the phrase Postdoctoral position in the Noonan lab in the subject line.
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...10-30-2026, 06:46 AM -
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM