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Bioinformatician: MPI-IE Freiburg, Germany

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  • Bioinformatician: MPI-IE Freiburg, Germany

    The position will be available in the Jenuwein group at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany (http://www.ie-freiburg.mpg.de/jenuwein). The Jenuwein group studies molecular mechanisms that establish and maintain heterochromatin in mammalian cells. There is a particular focus on the genome-wide regulation of repetitive element expression during mouse ES cell differentiation and in disease using a variety of experimental and next generation sequencing approaches. For these genomewide analyses, we seek an experienced bioinformatician, preferably with previous interest in chromatin biology and epigenetic control mechanisms. This Bioinformatician position is open immediately and initially funded for two years, with the possibility of extension.

    Your opportunities:
    As an embedded bioinformatician, you will have the opportunity to contribute
    directly to multiple research projects, from experimental design to data analysis and interpretation. This position also offers additional opportunities for participating in the Collaborative Research Center “Medical Epigenetics” (MEDEP). You will also interact with a strong, interdisciplinary bioinformatics and deep sequencing facility that provides access to a large Sequencing Facility (HiSeq3000, HiSeq2500, NextSeq), as well as a high-performance Data Center with Petabyte-scale storage solutions.

    Your tasks:
    Responsibilities include the bioinformatics analysis of genome-wide datasets,
    such as ChIP-seq and RNA-seq, as well as transcription factor motif analysis and analysis of other next-generation sequencing-based experiments. A strong understanding of epigenetic mechanisms of gene regulation will also be necessary, in order to process, analyze, and interpret a variety of datasets, focusing particularly on repetitive DNA elements and chromatin modifying factors.

    Your qualifications:
    We are looking for a dedicated and motivated team player with strong
    communication skills and good command of the English language, who has a MSc or PhD degree in bioinformatics or equivalent experience in a related field. The successful applicant will have proven experience in the analysis of genome-wide datasets and computational skills (python/perl, R/Bioconductor) in a Linux environnment. Knowledge of alignment programs (such as STAR), RepeatMasker, and data analysis and visualization tools in R will be necessary. A profound interest in epigenetics and repetitive DNA regulation will also be required.

    We offer:
    Based within a region that connects Germany, France and Switzerland, our
    institute hosts a vibrant community of international researchers, state-of-the-art facilities, and modern office spaces. A childcare facility is directly attached to the institute. At the heart of the Black Forest, Freiburg offers a family-friendly atmosphere and excellent recreational possibilities for cultural and outdoor activities. Salaries will be based on previous experience according to the German pay scale for civil service (TVöD) including health insurance and other social benefits.

    Application deadline: 15.02.2018
    Candidates should submit their full applications (including a 1 page motivation summary, CV, contact details of referees) to our home page: http://www.ie-freiburg.mpg.de/jobs.

    For informal inquiries please contact: [email protected]
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