PhD student (m/f/d) (TV-L E13, 65%)
Location: Rudolf Schönheimer Institute of Biochemistry (Faculty of Medicine)
and the Max Planck Institute for Evolutionary Anthropology Leipzig
Starting date: Spring/Summer 2019
Project: We are looking for a highly motivated PhD student for a 3-year position. The main project deals with comparative genomics of the ancient Steller’s Sea Cow Genome.
This project aims to identify pathways and genes involved in body size and energy storage by comparing the genomes of the ancient Steller’s sea cow, possibly the largest recent non-cetacean mammal, to the ones of the modern smaller sirenians, the dugong and the manatee. We also intend to detect how climate adaptation may shape genetic data by selection since unlike the modern sirenians, which are adapted to a warm climate, the Steller’s sea cow inhabited arctic environments. Additionally, we will build the phylogenetic tree of the sirenians, including genomic data of the hyraxes as a more distant outgroup than the African elephant.
A second running project deals with gene expression profiles of lipomas. By analyzing the differential expression of genes in lipoma versus matched normal subcutaneous adipose tissue we intend to identify genetic networks that are involved in lipid accumulation with a long-term goal of better understanding mechanisms of obesity.
At the Rudolf Schönheimer Institute of Biochemistry (Faculty of Medicine) we aim to understand medicine in the context of evolution. Leipzig University developed a major research focus in obesity. The two projects the PhD student is involved in inquires the same question using different perspectives and techniques.
Collaboration Partners: The project offers stimulating interactions and training opportunities including the Human Genetics Institute in Leipzig, the Institute for Biochemistry and Biology, Department of Mathematics and Natural Sciences, Potsdam University, and the Department of Bioinformatics and Genetics of the Swedish Museum of Natural History.
Profile of candidate’s qualifications: If you are highly motivated, fascinated by evolution and translating the findings to modern medicine, this may be the right position for you. Programming experience in R, python, and C++, as well as working in Linux environment will be of benefit.
Our offer:
• a supportive and international working environment
• access to cutting edge genomics, computing, and research facilities
• the chance to pursue fundamental research of medical relevance
• enrollment and graduation within the International Max Planck Research Schools (IMPRS) Programme
Interested? Please send your full application as a PDF to [email protected]
Location: Rudolf Schönheimer Institute of Biochemistry (Faculty of Medicine)
and the Max Planck Institute for Evolutionary Anthropology Leipzig
Starting date: Spring/Summer 2019
Project: We are looking for a highly motivated PhD student for a 3-year position. The main project deals with comparative genomics of the ancient Steller’s Sea Cow Genome.
This project aims to identify pathways and genes involved in body size and energy storage by comparing the genomes of the ancient Steller’s sea cow, possibly the largest recent non-cetacean mammal, to the ones of the modern smaller sirenians, the dugong and the manatee. We also intend to detect how climate adaptation may shape genetic data by selection since unlike the modern sirenians, which are adapted to a warm climate, the Steller’s sea cow inhabited arctic environments. Additionally, we will build the phylogenetic tree of the sirenians, including genomic data of the hyraxes as a more distant outgroup than the African elephant.
A second running project deals with gene expression profiles of lipomas. By analyzing the differential expression of genes in lipoma versus matched normal subcutaneous adipose tissue we intend to identify genetic networks that are involved in lipid accumulation with a long-term goal of better understanding mechanisms of obesity.
At the Rudolf Schönheimer Institute of Biochemistry (Faculty of Medicine) we aim to understand medicine in the context of evolution. Leipzig University developed a major research focus in obesity. The two projects the PhD student is involved in inquires the same question using different perspectives and techniques.
Collaboration Partners: The project offers stimulating interactions and training opportunities including the Human Genetics Institute in Leipzig, the Institute for Biochemistry and Biology, Department of Mathematics and Natural Sciences, Potsdam University, and the Department of Bioinformatics and Genetics of the Swedish Museum of Natural History.
Profile of candidate’s qualifications: If you are highly motivated, fascinated by evolution and translating the findings to modern medicine, this may be the right position for you. Programming experience in R, python, and C++, as well as working in Linux environment will be of benefit.
Our offer:
• a supportive and international working environment
• access to cutting edge genomics, computing, and research facilities
• the chance to pursue fundamental research of medical relevance
• enrollment and graduation within the International Max Planck Research Schools (IMPRS) Programme
Interested? Please send your full application as a PDF to [email protected]