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Related Articles Probabilistic resolution of multi-mapping reads in massively parallel sequencing data using MuMRescueLite.
Bioinformatics. 2009 Jul 15;
Authors: Hashimoto T, de Hoon MJ, Grimmond SM, Daub CO, Hayashizaki Y, Faulkner GJ
SUMMARY: Multi-mapping sequence tags are a significant impediment to short read sequencing platforms. These tags are routinely omitted from further analysis, leading to experimental bias and reduced coverage. Here we present MuMRescueLite, a low-resource requirement version of the MuMRescue software that has been used by several next generation sequencing projects to probabilistically reincorporate multi-mapping tags into mapped short read data. Availability and implementation: MuMRescueLite is written in Python; executables and documentation are available from http://genome.gsc.riken.jp/osc/english/software/. CONTACT: [email protected].
PMID: 19605420 [PubMed - as supplied by publisher]
More...
Related Articles Probabilistic resolution of multi-mapping reads in massively parallel sequencing data using MuMRescueLite.
Bioinformatics. 2009 Jul 15;
Authors: Hashimoto T, de Hoon MJ, Grimmond SM, Daub CO, Hayashizaki Y, Faulkner GJ
SUMMARY: Multi-mapping sequence tags are a significant impediment to short read sequencing platforms. These tags are routinely omitted from further analysis, leading to experimental bias and reduced coverage. Here we present MuMRescueLite, a low-resource requirement version of the MuMRescue software that has been used by several next generation sequencing projects to probabilistically reincorporate multi-mapping tags into mapped short read data. Availability and implementation: MuMRescueLite is written in Python; executables and documentation are available from http://genome.gsc.riken.jp/osc/english/software/. CONTACT: [email protected].
PMID: 19605420 [PubMed - as supplied by publisher]
More...