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single-cell sequencing
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  • Single-Cell Sequencing at an Inflection Point: Early Impacts of New Platforms and Emerging Trends



    With the launch of new single-cell sequencing platforms in 2026, the field stands at an exciting inflection point. This article surveys the most impactful advances in the field and discusses how they’re reshaping research in cancer, immunology, and beyond.


    Introduction

    Single-cell sequencing technologies have undergone remarkable advances over the past decade, transitioning from low-throughput experimental approaches to highly scalable platforms capable of...
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    Last edited by SEQadmin2; 05-26-2026, 09:50 AM.

  • Modern Methods and Techniques in Single-Cell Sequencing

    Modern Methods and Techniques in Single-Cell Sequencing





    Single-cell sequencing has become a transformative tool in biological research by providing scientists with the ability to detect cellular heterogeneity. The evolution of this technology has led to its widespread adoption, resulting in a seemingly endless list of publications, each emphasizing insights gained from its application. In this article, we’ll briefly review several key advancements in single-cell sequencing that have led to its continual rise.

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  • A Brief Overview and Common Challenges in Single-cell Sequencing Analysis


    ​​​​​​The introduction of single-cell sequencing has advanced the ability to study cell-to-cell heterogeneity. Its use has improved our understanding of somatic mutations1, cell lineages2, cellular diversity and regulation3, and development in multicellular organisms4. Single-cell sequencing encompasses hundreds of techniques with different approaches to studying the genomes, transcriptomes, epigenomes, and other omics of individual cells. The analysis of single-cell sequencing data i...

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  • Introduction to Single-Cell Sequencing

    Introduction to Single-Cell Sequencing

    Single-cell sequencing is a technique used to investigate the genome, transcriptome, epigenome, and other omics of individual cells using high-throughput sequencing. This technology has provided many scientific breakthroughs and continues to be applied across many fields, including microbiology, oncology, immunology, neurobiology, precision medicine, and stem cell research.

    The advancement of single-cell sequencing began in 2009 when Tang et al. investigated the single-cell transcriptomes
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