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SEQadmin2 started a topic Long-Read Sequencing Uncovers Cancer Mutations Conventional Testing Missedin NewsLong-Read Sequencing Uncovers Cancer Mutations Conventional Testing Missed
The University of Michigan’s Oncology Sequencing Program, known as MiOncoSeq, analyzes DNA and RNA from patients’ tumors and healthy tissue to find... -
Chemotherapy Leaves Detectable DNA Signatures in Childhood Tumors
A study led by The Hospital for Sick Children (SickKids), published in Nature, found that nearly half of childhood tumors treated with common chemotherapies... -
Cancer Drug Resistance: The Lingering Barrier to Rising Survival
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is... -
Single-Cell Sequencing at an Inflection Point: Early Impacts of New Platforms and Emerging Trends
With the launch of new single-cell sequencing platforms in 2026, the field stands at an exciting inflection point. This article surveys the most impactful advances in the field and discusses how they’re reshaping research in cancer, immunology, and beyond.
Introduction
Single-cell sequencing technologies have undergone remarkable advances over the past decade, transitioning from low-throughput experimental approaches to highly scalable platforms capable of...Last edited by SEQadmin2; 05-26-2026, 09:50 AM. -
Multiomics in the Era of Translational and Precision Medicine
Genomics has provided actionable clinical information, helping diagnose rare diseases, identify tumor mutations linked to treatment resistance, and find new drug targets.
But clinicians often face a problem: two tumors with the same mutation can respond differently to chemotherapy, and two patients with the same symptoms can carry entirely different DNA alterations.
The reason lies in the complexity of disease regulation. Changes in splicing, transcription,...Last edited by SEQadmin2; 03-23-2026, 08:58 AM. -
Decoding the Tumor Microenvironment with Next-Generation Sequencing
Cancer is increasingly understood as an ecosystem in which tumor cells co-evolve with immune, stromal, and vascular components of the surrounding tumor microenvironment (TME). These interactions affect disease progression, therapeutic response, and the emergence of resistance. Yet, the molecular mechanisms underlying these processes have long been difficult to resolve. Next-generation sequencing (NGS) technologies now enable high-resolution analysis of this dynamic landscape....Last edited by SEQadmin2; 03-23-2026, 05:13 AM. -
Exploring the Dynamics of the Tumor Microenvironment
The complexity of cancer is clearly demonstrated in the diverse ecosystem of the tumor microenvironment (TME). The TME is made up of numerous cell types and its development begins with the changes that happen during oncogenesis. “Genomic mutations, copy number changes, epigenetic alterations, and alternative gene expression occur to varying degrees within the affected tumor cells,” explained Andrea O’Hara, Ph.D., Strategic Technical Specialist at Azenta. “As... -
Advanced Tools Transforming the Field of Cytogenomics
At the intersection of cytogenetics and genomics lies the exciting field of cytogenomics. It focuses on studying chromosomes at a molecular scale, involving techniques that analyze either the whole genome or particular DNA sequences to examine variations in structure and behavior at the chromosomal or subchromosomal level. By integrating cytogenetic techniques with genomic analysis, researchers can effectively investigate chromosomal abnormalities related to diseases, particularly... -
How RNA-Seq is Transforming Cancer Studies
Cancer research has been transformed through numerous molecular techniques, with RNA sequencing (RNA-seq) playing a crucial role in understanding the complexity of the disease. Maša Ivin, Ph.D., Scientific Writer at Lexogen, and Yvonne Goepel Ph.D., Product Manager at Lexogen, remarked that “The high-throughput nature of RNA-seq allows for rapid profiling and deep exploration of the transcriptome.” They emphasized its indispensable role in cancer research, aiding in biomarker... -
Job:Senior Postdoctoral Research Scientist - Bioinformatics in Oxford
https://dub.sh/licrpd2
Senior Postdoctoral Research Scientist - Bioinformatics
Ludwig Institute for Cancer Research, Old Road...Last edited by olin0151; 01-19-2023, 06:51 AM. -
Genetic Testing for Cancer- Creative Biolabs
Creative Biolabs is skilled in NGS-based cancer research. We support one-stop cancer research services based on a variety of sequencing technologies.... -
Senior Postdoc/Bioinformatician Research Fellow @ UEA, Norwich, UK
Applications are invited for the post of Bioinformatician Research Fellow to undertake a leading role in the next generation sequencing Pan-Prostate Cancer... -
Research scientist in bioinformatics in Sweden
At Protein Structure and Bioinformatics Group (http://structure.bmc.lu.se/) at Lund University, Sweden we are recruiting a research scientist/postdoctoral... -
Postdoctoral Research Associate at Texas A&M University, Houston campus @TMC
The institute of biosciences and technology (IBT) at Texas A&M University College of Medicine, is an internationally recognized leader in biomedical... -
Genomic Medicine Conference in Copenhagen
The sixth annual GENOMIC MEDICINE 2019 NORDIC conference will take place at the Kennedy Centre at Rigshospitalet in Copenhagen on 13th & 14th November....
