RNA-binding proteins (RBPs) regulate the expression of thousands of transcripts, and some are reported to be involved in human tumorigenesis.
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Pan-Cancer Patterns of RNA-Binding Proteins in ~7000 tumor RNA-seq samples
Last edited by yjhua2110; 02-02-2018, 03:10 AM. -
Does reference genome contains alleles?
Hi,
I'm really confused about this; we have two almost same copy of genes (alleles) so when sequencing the genome that means there must... -
Maximum # of copies in a cluster?
Hi all,
I am just wondering why the # of DNA copies in each cluster is capped between 1000-2000.
Is this just due to the... -
CNV detection tools for non-human genomes
Hi all,
I'm very new to the world of genomics and CNVs so forgive me if my question is a bit basic.
I will be looking into detecting... -
Paralleling Control-FREEC chromosome by chromosome
I'm wondering if anyone is an expert on Control-FREEC here.
I've used this config file to run Control-FREEC on a tumor-normal WGS data:... -
Copy number variation in cancer WGS
Hi guys,
I am looking at some whole genome sequencing (WGS) for tumor-normal pairs, and I want to find somatic copy number alteration... -
Patchwork - allele-specific somatic CNAs in cancer (WGS)
We have developed an R package for allele-specific copy number analysis of whole genome sequenced tumor tissue, capable of handling normal cell content... -
Manipulating normal samples for CNV analysis
Dear all,
I have exome sequence data for about 100 patients. I found some tools like VarScan, ExomeCNV etc for CNV analysis. But they all... -
Control-FREEC: a tool for assessing copy number and allelic content using NGS data
Control-FREEC enables automatic calculation of copy number and allelic content profiles from next generation sequencing data, and consequently predicts... -
Copy number analysis using 454 data
Hi,
I am pretty new to sequence analysis in general, but I was wondering if anyone know how to identify amplifications and deletions from... -
exome copy number and LOH
Hi folks,
Can anyone recommend a good tool for exome copy number analysis on Illumina data?
Ideally, but not necessarily, it would... -
CNV analysis on Illumina / Solid genomes
Hi all,
I had a look at the wiki and I see there are many tools available for getting copy number changes from read alignments. I am...
