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  • Manipulating normal samples for CNV analysis

    Dear all,

    I have exome sequence data for about 100 patients. I found some tools like VarScan, ExomeCNV etc for CNV analysis. But they all need normal individual data also. Now I managed to get 10 normal samples. My question is -> should I randomly select any 1 normal sample for CNV analysis or is there any way to use all these normal samples as 1 sample?

    Any suggestions?

    Thanks
    Vikas

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