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translational research
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  • Multiomics in the Era of Translational and Precision Medicine

    • Published: 03-23-2026, 05:07 AM
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    in Articles

    Multiomics in the Era of Translational and Precision Medicine



    Genomics has provided actionable clinical information, helping diagnose rare diseases, identify tumor mutations linked to treatment resistance, and find new drug targets.

    But clinicians often face a problem: two tumors with the same mutation can respond differently to chemotherapy, and two patients with the same symptoms can carry entirely different DNA alterations.

    The reason lies in the complexity of disease regulation. Changes in splicing, transcription,...
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    Last edited by SEQadmin2; 03-23-2026, 08:58 AM.

  • Population Genomics: Applications in Healthcare, Conservation, Agriculture, and More

    • Published: 03-09-2026, 06:34 AM
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    in Articles

    Population Genomics: Applications in Healthcare, Conservation, Agriculture, and More


    Foundation, co-evolution with NGS, and impact

    Population genomics is the use of DNA data from entire populations to understand the genetic makeup of a group of individuals, human or otherwise. We previously covered the basics of population genomics and how next-generation sequencing (NGS) expanded the field here.1 Since then, population genomics has co-evolved with NGS to achieve measurable impacts in several areas.

    This article will cover:

    ● How    ...
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    Last edited by SEQadmin2; 03-09-2026, 07:49 AM.

  • Decoding the Tumor Microenvironment with Next-Generation Sequencing

    • Published: 02-23-2026, 11:07 AM
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    Decoding the Tumor Microenvironment with Next-Generation Sequencing




    Cancer is increasingly understood as an ecosystem in which tumor cells co-evolve with immune, stromal, and vascular components of the surrounding tumor microenvironment (TME). These interactions affect disease progression, therapeutic response, and the emergence of resistance. Yet, the molecular mechanisms underlying these processes have long been difficult to resolve. Next-generation sequencing (NGS) technologies now enable high-resolution analysis of this dynamic landscape....
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    Last edited by SEQadmin2; 03-23-2026, 05:13 AM.

  • NGS Advances as Tool for Synthetic Biology DBTL Cycle

    • Created by: SEQadmin2
    • Published: 02-13-2026, 10:34 AM
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    in Articles

    NGS Advances as Tool for Synthetic Biology DBTL Cycle







    Synthetic biology has advanced quickly in the last decade, and a lot of that is because of next-generation sequencing (NGS). In synthetic biology, engineering principles are applied to biological systems, to modify or create new biological organisms or molecules. Because of this, the working paradigm is the design-build-test-learn (DBTL) cycle.

    With the instructions to every organism, system, or molecule being encoded in DNA, NGS is crucial    ...
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    Last edited by SEQadmin2; 03-23-2026, 05:14 AM.
  • Bruker
    started a topic A Streamlined Approach to Bulk RNA and Protein Multiomics Profiling
    in Sequencing Resources

    A Streamlined Approach to Bulk RNA and Protein Multiomics Profiling

    As life science research becomes more integrated and systems-focused, single-modality profiling can fall short in characterizing complex biological systems....
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    Last edited by Bruker; 06-23-2025, 08:21 AM.
    • Bruker
      started a topic Screening of RNA-seq Discoveries with nCounter Targeted Gene Expression Analysis
      in Sequencing Resources

      Screening of RNA-seq Discoveries with nCounter Targeted Gene Expression Analysis




      Modern discovery research frequently begins with comprehensive techniques such as whole-transcriptome sequencing (RNA-seq) to reveal...
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      Last edited by Bruker; 04-07-2025, 06:35 AM.
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