Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • odoyle81
    Member
    • Aug 2011
    • 31

    #1

    SNPs to genotypes file?

    Is there an easy way to convert a set of SNPs (in hapmap or vcf format) into a genotype file that could be used by something like R/qtl?
    By a genotype file I mean something where columns are markers, rows are different lines, and the data is coded as either A (parent 1), B (parent 2), or H (het):
    marker1 marker2
    parent1 A A
    parent2 B B
    line1 A B
    line2 B A
    line3 H A

    I do have the calls for each parent.. but these are different than the reference that was used to generate the hapmap/vcf files.
    Seems like I could write a script to do this, or use excel, but surely there is a tool out there for this sort of thing?

    Thanks!

Latest Articles

Collapse

  • SEQadmin2
    16S/ITS Profiling vs. Shotgun Metagenomics: What Changes in Your Workflow?
    by SEQadmin2




    NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...
    Today, 06:46 AM
  • SEQadmin2
    Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
    by SEQadmin2



    Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

    Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating
    ...
    10-14-2026, 09:55 AM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by SEQadmin2, 10-28-2026, 09:57 AM
0 responses
22 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-28-2026, 09:51 AM
0 responses
15 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-22-2026, 11:13 AM
0 responses
68 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-22-2026, 10:48 AM
0 responses
48 views
0 reactions
Last Post SEQadmin2  
Working...