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Platform agnostic discussions about scientific applications of sequencing data

Forums Topics Posts Last Post
Sample Prep / Library Generation
Techniques and protocol discussions on sample preparation, library generation, methods and ideas
Topics: 2,174 Posts: 9,805
2,174 9,805
Single Cell Sequencing
Techniques, discussions, and applications of single cell sequencing.
Topics: 1 Posts: 1
1 1
Genomic Resequencing
Variant discovery in previously sequenced genomes/regions
Topics: 277 Posts: 990
277 990
De novo discovery
Wandering without a reference? Post here
Topics: 341 Posts: 1,700
341 1,700
Metagenomics
Ever wonder what's growing in that hot spring or glacier?
Topics: 265 Posts: 837
265 837
harbortc
Epigenetics
Any non-primary sequence heritable modification of genetic material. ChIP-SEQ, DNA methylation (Bisulfite-SEQ), chromatin modifications (methylation, acetylation, etc), non coding RNA.
Topics: 355 Posts: 1,576
Last Post: DMR simulator
355 1,576
malonzm1
RNA Sequencing
Application of sequencing to RNA analysis (RNA-Seq, whole transcriptome, SAGE, expression analysis, novel organism mining, splice variants)
Topics: 2,848 Posts: 11,388
2,848 11,388
Clinical Sequencing
Discuss issues unique to clinical sequencing.
Topics: 39 Posts: 104
39 104

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Recent Articles

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  • seqadmin
    A Brief Overview and Common Challenges in Single-cell Sequencing Analysis
    by seqadmin


    ​​​​​​The introduction of single-cell sequencing has advanced the ability to study cell-to-cell heterogeneity. Its use has improved our understanding of somatic mutations1, cell lineages2, cellular diversity and regulation3, and development in multicellular organisms4. Single-cell sequencing encompasses hundreds of techniques with different approaches to studying the genomes, transcriptomes, epigenomes, and other omics of individual cells. The analysis of single-cell sequencing data i...

    01-24-2023, 01:19 PM
  • seqadmin
    Introduction to Single-Cell Sequencing
    by seqadmin
    Single-cell sequencing is a technique used to investigate the genome, transcriptome, epigenome, and other omics of individual cells using high-throughput sequencing. This technology has provided many scientific breakthroughs and continues to be applied across many fields, including microbiology, oncology, immunology, neurobiology, precision medicine, and stem cell research.

    The advancement of single-cell sequencing began in 2009 when Tang et al. investigated the single-cell transcriptomes
    ...
    01-09-2023, 03:10 PM
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