Hi all!
i'm working on a project based on the whole-genome resequencing of pooled populations with the aim of detecting selective sweeps. Initially, we look at three already published and similar works where no more than 20 individuals were included in each pool and sequenced to 5-10x coverage. But recently I have read som papers focused on pooling strategy for population genomics and they talk about a minimum of 25 individuals (diplod) sequenced to at least 20-30x, which is significantly more economic effort.
Can someone help me with this issue?
thanks!!
i'm working on a project based on the whole-genome resequencing of pooled populations with the aim of detecting selective sweeps. Initially, we look at three already published and similar works where no more than 20 individuals were included in each pool and sequenced to 5-10x coverage. But recently I have read som papers focused on pooling strategy for population genomics and they talk about a minimum of 25 individuals (diplod) sequenced to at least 20-30x, which is significantly more economic effort.
Can someone help me with this issue?
thanks!!
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