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  • mfasold
    Junior Member
    • Jun 2011
    • 1

    #1

    Introducing DARIO, a web service for the analysis of small RNA-seq data

    Hi,

    we would like to point the community to a web tool we have recently developed.

    DARIO is a web service for the analysis of short RNAs from high throughput sequencing data. It features
    • fast and convenient analysis of small RNA-seq data (short RNA-seq protocol)
    • no dependencies to any sequencing platform or mapping tool (convert from common SAM format)
    • differential expression: direct comparison of expressions from several DARIO runs due to RPM normalization
    • upload of own annotations or regions of interest
    • prediction of new putative ncRNAs using a machine learning approach
    • additional validation of predicted ncRNAs using RNAz


    Files can be uploaded in BED or BAM format. The website currently supports seven assemblies of six species: human (hg18, hg19), rhesus monkey (rheMac2), mouse (mm9), fruit fly (dm3), worm (ce6) and zebrafish (danRer6).

    Any comments and suggestions appreciated.

    URL: http://dario.bioinf.uni-leipzig.de/

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