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  • tasteandsee
    Junior Member
    • Jun 2011
    • 1
    #1

    TopHat closure based search and coverage based search

    Hi,
    I am very new to NGS analysis and TopHat. Could someone please explain to me what closure based search and coverage based search exactly mean? I read the manuscript and the manual, but still couldn't figure it out.
    Thanks,
    TS
    Tags: tophat options
    • glados
      Member
      • Mar 2012
      • 59
      #2
      I wonder this as well. It's really difficult to find information about these two parameters in tophat.

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