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  • NicoBxl
    not just another member
    • Aug 2010
    • 264

    Align sequence on secondary strcuture

    Hi guys,

    Anyone knows if a tool to align sequence (RNA, DNA) on a secondary structure exists ? It's only for visualization of the alignment on a known structure.

    Thanks,

    N.
  • sphil
    Senior Member
    • Apr 2010
    • 192

    #2
    For secondary structure based alignments look at http://expasy.org/tools/#secondary.
    Hope that helps. Else if you want to do this for tertiary u can use modeller, for instance.

    best,


    Phil

    Comment

    • NicoBxl
      not just another member
      • Aug 2010
      • 264

      #3
      Thanks, but it's ok for the structure (I have it). What I want to do is align sequencing reads on this structure and see where the reads aligned on it.

      Comment

      • NicoBxl
        not just another member
        • Aug 2010
        • 264

        #4
        nobody knows ? I think such a tool will be useful

        Comment

        • me_myself_andI
          Member
          • Nov 2010
          • 30

          #5
          In the case of RNA you could probably use Infernal and an Rfam model of your choice to align it against your RNA in question.


          Andreas

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