Before I start working on this, does anyone have a tool that identifies which build a set of gene coordinates belongs to from among the human genome builds? I have run into several papers where the authors do not identify the build, and it is clearly not the latest. The idea would be to take a large sample of the coordinates of unknown build and screen them against the last X number of builds to find 100% exact matches. Once known, then the data can easily be lifted from build to build using Galaxy.
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Professor of Pharmaceutical Sciences at Southern Illinois University. Subject of the Personal Genomes Project with CGI genome sequencing, funded by a university seed grant. Annotated human and mouse genomes at the Washington University (St. Louis) GSC during Bob Waterston's tenure. Worked in nematode gene discovery at Divergence, Inc. Recent NSF grant in yeast recombinant genetics. Teach pharmacogenomics, human genomics and pharmaceutical biotechnology.
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM