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  • aleferna
    Senior Member
    • Sep 2009
    • 121
    #1

    Whats the M in chromosome 3?

    anybody knows whats with the letter M in position
    chr3:60830521-60830580 ?

    Who do you call if there is an error in the official human genome?


    ftp://ftp.ncbi.nlm.nih.gov/genbank/g...STA/chr3.fa.gz
    Tags: None
    • swbarnes2
      Senior Member
      • May 2008
      • 910
      #2
      Generally, 'M' means that the letter in question is either an A or a C. So it's probably not a typo, maybe they couldn't determine which letter it was from their data.

        Comment

        • Jon_Keats
          Senior Member
          • Mar 2010
          • 279
          #3
          Seems to depend on the source of the genome files. NCBI, seems to still have them, UCSC has always convered to Ns, Ensembl had them for a bit (in 1kg ref files for instance) but disappeared in later versions.

          See this previous thread
          Who let M's and R's in the Genome - SEQanswers
          http://seqanswers.com/forums/showthread.php?t=6691
          Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc

            Comment

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