I don't think it does as the Tophat manual states that it does not mix the single read and paired end reads together, hence how could it map single reads when starting out with PE. However this might be wrong. Does anyone know if this is true or not? Thanks.
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by SEQadmin2
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...-
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10-14-2026, 09:55 AM -
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