filtering the variants

[kjaja]

Hi All,

I have cases and controls the we exome sequenced and the question is what are the variants that we see in cases but not in controls (some these individuals are related). I want to know your opinions and if there are tools out there that can be used to filter the variants and answer the question.


thanks

[Knaus]

Try to upload the data onto an aacount of yours at www.gene-talk.de
set up a pedigree (affected and unaffected) for your patient data and filter for dominant variants.
you will be likely to find annotations and informations about some variants