I am a beginner. I want to learn BWA and MAQ. My question is that where I can download the ref.fasta and read.fastq file, which should be a small genome because the small memory in my computer.
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Look for reference genomes in NCBI. MAQ is nice because it does a lot of things for you, but it's been superseded by other software suites. bwa for alignment and either SAMTools or GATK would be more useful in the long run. MAQ's algorithm is also much slower than bwa, but it won't matter much for something small, like a bacterium. -
swbarnes2,
Thanks a lot.Comment
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
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