Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Create vcf tribble index?

    Hi, I'm using the GaTK to call variants, and afterward I somehow managed to delete some of the .vcf.idx index files. Without those files the GaTK can't read the vcf files. Is there a way to (re-) build the .idx indexes without re-running the UnifiedGenotyper? Couldn't find one in the GaTK documentation. (I read about tabix, but he requires bgzipped input, which I'm not sure the GaTK can handle)
    Thanks!

  • #2
    You can generate the index using igvtools, either from the command line or from the IGV gui.

    Actually, the command line version never works for me. It gives the error, "Exception in thread "main" org.broad.tribble.TribbleException$InvalidHeader: Your input file has a malformed header: We never saw a header line specifying VCF version". But running the tool from inside IGV has no problem.

    Comment


    • #3
      I run the tool from inside IVG and it gives the error: "Your input file has a malformed header:The FORMAT field was provided but there is on genotype/sample data"

      Do you know how to fix this?

      Comment

      Latest Articles

      Collapse

      • seqadmin
        Essential Discoveries and Tools in Epitranscriptomics
        by seqadmin




        The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...
        04-22-2024, 07:01 AM
      • seqadmin
        Current Approaches to Protein Sequencing
        by seqadmin


        Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
        04-04-2024, 04:25 PM

      ad_right_rmr

      Collapse

      News

      Collapse

      Topics Statistics Last Post
      Started by seqadmin, Yesterday, 08:47 AM
      0 responses
      12 views
      0 likes
      Last Post seqadmin  
      Started by seqadmin, 04-11-2024, 12:08 PM
      0 responses
      60 views
      0 likes
      Last Post seqadmin  
      Started by seqadmin, 04-10-2024, 10:19 PM
      0 responses
      59 views
      0 likes
      Last Post seqadmin  
      Started by seqadmin, 04-10-2024, 09:21 AM
      0 responses
      54 views
      0 likes
      Last Post seqadmin  
      Working...
      X