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  • doc.ramses
    Member
    • Jan 2011
    • 26

    vcf filtering

    I have a multi sample vcf file. How can I filter only for overlapping snps within this one vcf file.
    As far as I understand, intersectBed and vcf-isec only work for different files.

    Thanks a lot for your help!
  • quinlana
    Senior Member
    • Sep 2008
    • 119

    #2
    Why not use those tools and intersect the file to itself?

    Comment

    • doc.ramses
      Member
      • Jan 2011
      • 26

      #3
      hm, but how can a target certain samples ? lets say I have a vcf with 10 samples. how to filter only for variants overlapping in samples 1 sample 3 and sample 7 ?

      Comment

      • Bukowski
        Senior Member
        • Jan 2010
        • 388

        #4
        Originally posted by doc.ramses View Post
        hm, but how can a target certain samples ? lets say I have a vcf with 10 samples. how to filter only for variants overlapping in samples 1 sample 3 and sample 7 ?
        Why not use vcf-subset to leave the samples in separate vcf's and then use vcf-isec?

        Comment

        • doc.ramses
          Member
          • Jan 2011
          • 26

          #5
          Originally posted by Bukowski View Post
          Why not use vcf-subset to leave the samples in separate vcf's and then use vcf-isec?
          This is the solution I'm using, now. But with a growing sample number, this is really annoying. I thought there must be a more elegant one doing this in one step.

          Comment

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