Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • dicatoma
    Junior Member
    • Nov 2010
    • 2

    #1

    Fusions false positives - using Breakdancer

    Dear all,

    I'm a phD student with no bioinformatic background.
    It's my first post here and hope someone can help me

    I've done whole genome sequencing on some cell lines (no match normal) and used Breakdancer to look for potential fusions/translocations.
    I'm using IGV to visually inspect the big list I received with the possible translocations. Though I'm coming across so many different patterns that I'm not sure if can say that they are real or not.

    Does anyone have more information/examples on how to exclude false positive by visual inspection?

    I've contacted IGV help, and this forum was recommended by them.
    Hope somenone can give me some help with this!

    Thanks
    Diana

Latest Articles

Collapse

  • SEQadmin2
    16S/ITS Profiling vs. Shotgun Metagenomics: What Changes in Your Workflow?
    by SEQadmin2





    NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification,...
    10-30-2026, 06:46 AM
  • SEQadmin2
    Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
    by SEQadmin2



    Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

    Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating
    ...
    10-14-2026, 09:55 AM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by SEQadmin2, Yesterday, 07:59 AM
0 responses
15 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 11-05-2026, 09:25 AM
0 responses
32 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 11-03-2026, 11:54 AM
0 responses
45 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-28-2026, 09:57 AM
0 responses
171 views
0 reactions
Last Post SEQadmin2  
Working...